Or as the game would be known in English (if it were real): Downtown Girls’ Hot-Blooded Story.
Actually, I shouldn't say the game isn't real; it is real, in that it exists, but it certainly isn't an official release. Instead, someone hacked Downtown Nekketsu Monogatari (aka River City Ransom) and replaced all of the game's male sprites with female ones. He/she then went a few steps further and made an actual cartridge and box for the title--and put the whole shebang up for sale on Yahoo! Auctions. The winning bidder handed over a whopping ¥25,510 (about $276) for it.
As cool as the game looks (a few screenshots can be seen at the bottom of its Yahoo! Auctions page), I think I'll stick with the original--which I bought ages ago for $5 via the Wii Virtual Console.