Especially when the cartridge used to create said USB drive is the Japanese version of Mario vs. Donkey Kong.
That's just one of the cute game-related creations I found while scanning etsy.com a few minutes ago.
Nearly as cute: this desk clock, made with a re-purposed Super Mario Bros./Duck Hunt cartridge. And then there's this needle-felted Green Slime figure. (I've always had a thing for Dragon Quest's slimes.)
See also: 'The perfect gift for the stinky gamer in your life'