I don't know about you, but I have an irrational, nostalgia-fueled reaction to the NES Zapper. That's funny to me, because I barely used the orange-and-gray peripheral I owned back in the day. Sure, I played Duck Hunt every now and then, but it definitely wasn't among my favorite games of the 8-bit era.
All that said, I think I'd be drawn to Aaron Jasinski's "The Duel" (below) even if I didn't have an irrational, nostalgic reaction to the Zapper.
This acrylic-on-wood painting can be purchased (here) for a mere $1,100, by the way. To see more of Jasinski's work, check out his blog or his deviantart page.